Etiometry’s commitment to clinically meaningful outcomes is also highlighted in three recent peer-reviewed studies

Clark et al., Journal of Pediatric Critical Care, Jan-Feb 2025

  • A single-center retrospective study out of Alabama found that using an automated spontaneous breathing trial (SBT) performance tool significantly improved key outcomes for pediatric cardiac surgery patients.
  • Analyzing 787 surgical hospitalizations in a tertiary cardiac ICU—581 before and 206 after the SBT tool was introduced—researchers observed a:
    • 30% reduction in postoperative time on ventilator 
    • 20% reduction in postoperative length of stay 

Gazit et al., Critical Care Medicine 2025, Volume 53 (7)

  • A multicenter study evaluated the impact of a Risk Analytics Clinical Decision Support tool on vasoactive infusion use following cardiac surgery. Conducted across three pediatric cardiac ICUs, the study included 775 infants who underwent surgery with cardiopulmonary bypass and received vasoactive infusions for at least six hours.
  • Results showed that the intervention group experienced:
    • 29% reduction in vasoactive infusion duration 
    • No significant differences were observed in cardiac ICU length of stay, cardiac arrest rates, or weaning failure.

Hames et al., Pediatric Critical Care Medicine, February 10, 2025.

  • A multicenter retrospective cohort study analyzed 736 neonates from 8 pediatric cardiac ICUs to investigate predictors of extubation failure (EF) after congenital cardiac surgery. EF was defined as reintubation within 48 hours of extubation and occurred in 13.9% of cases.
  • The study evaluated two physiologic risk analytics algorithms—IDO2 and IVCO2—in the two hours before extubation. Findings showed that:
    • Single ventricle anatomy significantly increased the odds of EF (OR 2.50).
    • High IDO2 (≥25) or high IVCO2 (≥50) were also associated with elevated EF risk (OR 1.77).
    • These results suggest that IDO2 and IVCO2 may be valuable tools for assessing extubation readiness and improving clinical decision-making in neonates following cardiac surgery.