Risk of over-diagnosis of hypotension in children: a comparative analysis of over 50,000 blood pressure measurements
Intensive Care Medicine
Authors: Ray S, Rogers L, Noren DP, Nadel S, Peters MJ, Inwald DP

Liberal oxygenation in paediatric intensive care: retrospective analysis of high-resolution SpO2 data
Intensive Care Medicine
Authors: Samiran Ray, L. Rogers, S. Raman, M. J. Peters, On behalf of the Oxy-PICU investigators

Disrupting Electronic Health Records Systems: The Next Generation
JMIR Medical Informatics
The health care system suffers from both inefficient and ineffective use of data. Data are suboptimally displayed to users, undernetworked, underutilized, and wasted. Errors, inefficiencies, and increased costs occur on the basis of unavailable data in a system that does not coordinate the exchange of information, or adequately support its use. Clinicians’ schedules are stretched to the limit and yet the system in which they work exerts little effort to streamline and support carefully engineered care processes. Information for decision-making is difficult to access in the context of hurried real-time workflows. This paper explores and addresses these issues to formulate an improved design for clinical workflow, information exchange, and decision making based on the use of electronic health records.
Author: Leo Anthony Celi, MD, MPH, MS

Daily Goals Formulation and Enhanced Visualization of Mechanical Ventilation Variance Improves Mechanical Ventilation Score
Respiratory Care Journal
The systematic implementation of evidence-based practice through the use of guidelines, checklists, and protocols mitigates the risks associated with mechanical ventilation, yet variation in practice remains prevalent. Recent advances in software and hardware have allowed for the development and deployment of an enhanced visualization tool that identifies mechanical ventilation goal variance. The aim of this research was to assess the utility of daily goal establishment and a computer-aided visualization of variance.
Authors: Brian K Walsh, Craig Smallwood, Jordan Rettig, Robert Kacmarek, John Thompson and John H Arnold

Towards Effective Data Utilization in Congenital Cardiac Critical Care
A chapter in the book Pediatrics and Congenital Cardiac Care
Critical care is among the most data-intensive fields in health care, with multiple sources of physiologic measurements that are tracked both continuously and intermittently for the purpose of guiding ongoing treatment. Clinicians have a limited capacity to convert this data into actionable information, and thus there is an ongoing effort to develop sophisticated analytic support systems.
Authors: Dimitar Baronov, Jesse Lock, Sam Phillips, Melvin C. Almodovar, Peter C. Laussen and Evan Butler

Risk Analytics and Outcome Prediction in Neonates Following Cardiac Surgery
Presented at the 10th International Conference of the Pediatric Cardiac Intensive Care Society
Assuring adequate systemic oxygen delivery (DO2) in critically ill patients is necessary to maintain or recover vital organ function, thus impacting patient outcomes. Consequently, it is important to reliably evaluate and monitor DO2 to optimize our understanding of the patient’s condition as well as the response to treatment.
Authors: Melvin C. Almodovar, Dimitar Baronov, Michael McManus, Evan Butler and Peter C. Laussen
Authors: Melvin C. Almodovar, Dimitar Baronov, Michael McManus, Evan Butler and Peter C. Laussen


Next-Generation Patient Monitor Powered by In-Silico Physiology
From the conference proceedings of the IEEE Engineering in Medicine and Biology Society
The goal of this paper is to introduce a next-generation patient monitoring technology that relies on objective and continuous data analytics to alleviate the data overload in the critical care unit.
Authors: Dimitar Baronov, Michael McManus, Evan Butler, Douglas Chung, and Melvin C. Almodovar

The Future of Critical Care Medicine : Integration and Personalization
Published by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc.
We must push critical care medicine to its limits by incorporating new technology, collaborating with other hospital departments, limiting protocolized care to units where well-trained intensivists are not available, and adopting more personalized medicine.
Author: Jean Louis Vincent

Excess Costs Associated with Complications and Prolonged Length of Stay After Congenital Heart Surgery
Published by the American Board of Thoracic Surgery
While there is an increasing emphasis on both optimizing quality of care and reducing health care costs, there are limited data regarding how to best achieve these goals for common and resource-intense conditions such as congenital heart disease. We evaluated excess costs associated with complications and prolonged length of stay (LOS) after congenital heart surgery in a large multicenter cohort.
Authors: Sara K. Pasquali, MD, Xia He, MS, Marshall L. Jacobs, MD, Samir S. Shah, MD, MSCE, Eric D. Peterson, MD, MPH, Michael G. Gaies, MD, MPH, Matthew Hall, PhD, J. William Gaynor, MD, Kevin D. Hill, MD, MS, John E. Mayer, MD, Jennifer S. Li, MD, MHS, Jeffrey P. Jacobs, MD

Daily Cost of an Intensive Care Unit Day: The Contribution of Mechanical Ventilation
Objective: To quantify the mean daily cost of intensive care, identify key factors associated with increased cost, and deter- mine the incremental cost of mechanical ventilation during a day in the intensive care unit.
Authors: Joseph F. Dasta, MSc, FCCM; Trent P. McLaughlin, PhD; Samir H. Mody, PharmD, MBA; and Catherine Tak Piech, MBA

The Cardiac Intensive Unit Perspective on Hemodynamic Monitoring of Oxygen Transport Balance
This paper discusses the importance of assessing the adequacy of oxygen delivery as the central tenant of cardiac intensive care.
Authors: PA Chechia and Peter C. Laussen